Bruce Randall Donald

Bruce Randall Donald

James B. Duke Professor of Computer Science

Please visit Bruce Donald's personal web page for up-to-date information, research, teaching, and publications. That website is hosted by the Departments of Computer Science, Chemistry, and Biochemistry at Duke University.

Appointments and Affiliations

  • James B. Duke Professor of Computer Science
  • Professor of Computer Science
  • Professor in the Department of Electrical and Computer Engineering
  • Professor of Biochemistry
  • Professor in the Department of Chemistry
  • Faculty Network Member of the Duke Institute for Brain Sciences
  • Bass Fellow

Contact Information

Research Interests

Computational Biology, Computational Chemistry, Structural Biology, Biochemistry, Protein Design, Drug Design, NMR of Biological Macromolecules, Microelectromechanical Systems (MEMS), Micro-robotics, Geometric Algorithms

In the News

Representative Publications

  • Zhou, Y; Donald, BR; Zeng, J, Parallel Computational Protein Design., Methods in molecular biology (Clifton, N.J.), vol 1529 (2017), pp. 265-277 [abs].
  • Ojewole, A; Lowegard, A; Gainza, P; Reeve, SM; Georgiev, I; Anderson, AC; Donald, BR, OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design., Methods in molecular biology (Clifton, N.J.), vol 1529 (2017), pp. 291-306 [abs].
  • Pan, Y; Dong, Y; Zhou, J; Hallen, M; Donald, BR; Zeng, J; Xu, W, cOSPREY: A Cloud-Based Distributed Algorithm for Large-Scale Computational Protein Design., Journal of Computational Biology, vol 23 no. 9 (2016), pp. 737-749 [10.1089/cmb.2015.0234] [abs].
  • Gainza, P; Nisonoff, HM; Donald, BR, Algorithms for protein design., Current Opinion in Structural Biology, vol 39 (2016), pp. 16-26 [10.1016/j.sbi.2016.03.006] [abs].
  • Jou, JD; Jain, S; Georgiev, IS; Donald, BR, BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design., Journal of Computational Biology, vol 23 no. 6 (2016), pp. 413-424 [10.1089/cmb.2015.0194] [abs].