Warren M. Grill

Image of Warren M. Grill

Bass Fellow

Our research is in the area of neural engineering: using engineering approaches to understand and control neural function. We work on fundamental questions and applied development in electrical stimulation of the nervous system to restore function to individuals with neurological impairment or injury.

Current projects include:
• understanding the mechanisms of and developing advanced approaches to deep brain stimulation to treat movement disorders,
• developing novel approaches to peripheral nerve electrical stimulation for restoration of bladder function, 
• understanding the mechanisms of and developing advanced approaches to spinal cord stimulation to treat chronic pain,
• understanding and controlling the cellular effects of transcranial magnetic stimulation, and
• design of novel electrodes and waveforms for selective stimulation of the nervous system.

Appointments and Affiliations
  • Bass Fellow
  • Professor of Biomedical Engineering
  • Professor in the Department of Electrical and Computer Engineering
  • Professor in Neurobiology
  • Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information:
  • Office Phone: (919) 660-5276
  • Email Address: warren.grill@duke.edu
  • Web Page:
Education:

  • Ph.D. Case Western Reserve University, 1995
  • M.S. Case Western Reserve University, 1992
  • B.S. Boston University, 1989

Research Interests:

Dr. Grill’s research interests and in neural engineering and neural prostheses and include design and testing of electrodes and stimulation techniques, the electrical properties of tissues and cells, and computational neuroscience with applications in restoration of bladder function, treatment of movement disorders with deep brain stimulation, and treatment of chronic pain.

Specialties:

Neuroengineering
Neural Prosthesis

Awards, Honors, and Distinctions:

  • Fellows. American Institute for Medical and Biological Engineering. 2007

Courses Taught:
  • BME 301L: Bioelectricity (AC or GE)
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • BME 515: Neural Prosthetic Systems (GE,EL,IM)
  • BME 791: Graduate Independent Study
  • BME 899: Special Readings in Biomedical Engineering
  • NEUROSCI 301L: Bioelectricity (AC or GE)
  • NEUROSCI 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • NEUROSCI 515: Neural Prosthetic Systems (GE,EL,IM)

Representative Publications: (More Publications)
    • Danziger, Z; Grill, WM, A neuron model of stochastic resonance using rectangular pulse trains., Journal of Computational Neuroscience, vol 38 no. 1 (2015), pp. 53-66 [10.1007/s10827-014-0526-4] [abs].
    • McGee, MJ; Grill, WM, Selective co-stimulation of pudendal afferents enhances bladder activation and improves voiding efficiency., Neurourology and Urodynamics, vol 33 no. 8 (2014), pp. 1272-1278 [10.1002/nau.22474] [abs].
    • Howell, B; Grill, WM, Evaluation of high-perimeter electrode designs for deep brain stimulation., Journal of Neural Engineering, vol 11 no. 4 (2014) [10.1088/1741-2560/11/4/046026] [abs].
    • Kent, AR; Grill, WM, Analysis of deep brain stimulation electrode characteristics for neural recording., Journal of Neural Engineering, vol 11 no. 4 (2014) [10.1088/1741-2560/11/4/046010] [abs].
    • Mueller, JK; Grigsby, EM; Prevosto, V; Petraglia, FW; Rao, H; Deng, ZD; Peterchev, AV; Sommer, MA; Egner, T; Platt, ML; Grill, WM, Simultaneous transcranial magnetic stimulation and single-neuron recording in alert non-human primates., Nature Neuroscience, vol 17 no. 8 (2014), pp. 1130-1136 [10.1038/nn.3751] [abs].